• br Results br Discussion The

  2018-10-24

  

  Results Discussion The development of miRNA-based therapy approaches has become one of the most attractive areas of tissue engineering (Lian et al., 2012). Recently, many studies reported that miRNAs are important regulators for the therapy or differentiation of stem cannabinoid receptor (Cho

• However in these models human hematopoietic

  2018-10-24

  

  However, in these models, human hematopoietic reconstitution is usually B-lymphoid dominant, and engraftment of human myeloid, erythroid, and megakaryocyte lineages is limited (Doulatov et al., 2012; Ito et al., 2012; Rongvaux et al., 2013; Yamauchi et al., 2013). This skewed reconstitution could be

• br Results br Discussion Here we performed genome

  2018-10-24

  

  Results Discussion Here we performed genome-wide ATAC-seq, ChIP-seq, and RNA-seq profiling to define the immediate-early molecular events that catalyze fibroblast-to-neuron reprogramming by NEUROG2 and small molecules. While NEUROG2 is sufficient to reprogram glial adenosine receptor antagonis

• As in mammals epithelial turnover in the

  2018-10-24

  

  As in mammals, epithelial turnover in the Drosophila intestine is also mediated by ISCs. Fly ISCs undergo cell division to renew themselves and give rise to transient cells, enteroblasts (EBs), which can differentiate into absorptive enterocytes (ECs) or secretory enteroendocrine (EE) cells. ISCs in

• Composites studied have the same inclusion particle

  2018-10-24

  

  Composites studied have the same inclusion particle size, the same percentage, but differ in values of spontaneous polarization and dielectric permittivity. When comparing interaction energies of inclusion particles (BaTiO3, PbTiO3, LiNbO3) and matrix (SС(NH2)2), it is supposed that internal field i

• To inspect the motion of a particle in

  2018-10-24

  

  To inspect the motion of a particle in bent crystals, the old coordinates of the points (x, y, z) in the simulated boxes are transformed into new (x′, y′, z′) by the following rule: where the parameter defines the shape of a bent crystal. The latter equation holds for a bending radius that suffici

• where a is a radius

  2018-10-24

  

  where a is a radius of the circular contact (probe); r is a distance from the center of the contact – probe place to the hemispherical contact; ρ is a resistivity of the area between the contacts. Spreading resistance R is well approximated for a homogeneous semi-infinite doped sample with resistan

• Aside from yield point change structural element

  2018-10-24

  

  Aside from yield point change, structural Z DEVD FMK Supplier refinement can also affect the melting temperature. The latter is determined experimentally for micro- and nanodisperse materials, but not as definitively as the yield point. For example, aggregate and powder metallic nanomaterials may h

• In the USAID Maternal Child Health

  2018-10-24

  

  In 2012, the USAID Maternal Child Health Integrated Program commissioned a comprehensive report on the state of “respectful maternity care” (RMC) across low and high resource countries (Reis et al., 2012). The authors concluded “safe motherhood must be expanded beyond the prevention of morbidity or

• br Introduction In order to obtain

  2018-10-24

  

  Introduction In order to obtain easy access to accurate material and Sulfo-NHS-LC-Biotin inventory data for the modelling of industrial bioprocesses at the early stages of process design, a Microsoft® Excel model has been developed, termed the CeBER Bioprocess Modeller (Centre for Bioprocess Eng

• The DHCR gene has been mapped

  2018-10-23

  

  The DHCR24 gene has been mapped to chromosome 1p32.3, a region commonly amplified in HCC and which may contribute to carcinogenesis (Yuan et al., 2003; Endo et al., 2009). Recently, two experienced mutations, Q88L and R311H, were identified in the DHCR24 gene in Korean HCC patients (Ahn et al., 201

• Interrogating the underlying pathophysiology prior to the fu

  2018-10-23

  

  Interrogating the underlying pathophysiology prior to the full-blown manifestations can help clarify some confounding effects. For example, extant neuroimaging research on established BP has suggested that the volume of gray matter (GM) decreases in the regions underpinning emotion processing and re

• br Author contributions br Acknowledgements br Introduction

  2018-10-23

  

  Author contributions Acknowledgements Introduction Diabetes type 2 is an epidemic public health problem. Poorly controlled diabetes results in accelerated microvascular disease and chronic debilitating morbidities and mortality (Beckman et al., 2002). Diabetic microvascular angiopathy is th

• Dengue is a climate sensitive mosquito borne viral disease

  2018-10-23

  

  Dengue is a climate sensitive mosquito-borne viral disease that is generally found in the tropics and subtropics (Murray et al., 2013). According to the World Health Organization (World Health Organization (WHO), 2012) and recent assessment on global burden of diseases (GBD2013) (Murray et al., 2015

• The cAMP pathway has been

  2018-10-23

  

  The cAMP pathway has been implicated in physiological and pathological learning, but cognitive enhancement in healthy individuals has not been previously observed. In Drosophila, cAMP signaling during development is required for fine-tuning mushroom-body output neurons, a key component of learning a

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