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A topological property P is said to be
2020-07-29
A topological property P is said to be cut point hereditary [3] if whenever a space X has property P, then, for every there exists some T16Ainh - A01 of such that each of and has property P. A space X is called connected ordered topological space (COTS) [5] if it is connected and has the prop
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br Material and methods br
2020-07-29
Material and methods Results Discussion Acknowledgements This work was supported by grants from the Agence Nationale de la Recherche (ANR) (ANR07-PHYSIO-008-2 and BLAN 2010-111201), and by a grant from the BHFZ (Bayerisch-Französisches Hochschulzentrum; FK-13/09). S. L\'Hoste and O. Andr
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br Cocaine dependence is common with over million actively c
2020-07-28
Cocaine dependence is common, with over 1.5 million actively cocaine-dependent people in 2011 who have substantial social and economic morbidity from it, but it has no US Food and Drug Administration-approved pharmacotherapy (, ). In methadone maintenance programs rates of cocaine use range from 3
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br Methods br Results br
2020-07-28
Methods Results Discussion Reduced memory capacity is a core cognitive symptom of schizophrenia [2,[4], [5], [6], [7], [8],[11], [12], [13], [14], [15], [16], [17], [18], [19]] and an early marker of ageing-associated cognitive decline [17]. In this study, using a pharmacological approach,
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With respect to the duration
2020-07-28
With respect to the duration of acid-etching, few studies have shown that ceramic etching with a 5% HF during for 2–3 min is sufficient to dissolve the glassy phase [32], increasing roughness and creating a surface more favourable to bonding. Similarly, a previous study [33] showed that 10% hydroflu
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The non fused pyrimidin one hits
2020-07-28
The non-fused pyrimidin-4(3)-one hits followed the general formula presented in . The tri-substituted morpholino derivative (IC=0.92μM) and the tetra-substituted bromophenyl derivative (IC=0.37μM) were the most active compounds in this cluster, and were among the most efficient binders, with disp
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Interestingly resveratrol protects from alcohol induced fatt
2020-07-28
Interestingly, resveratrol protects from alcohol-induced fatty liver disease in part by increasing fatty SP2509 receptor oxidation as observed through greater B-OHB coupled with enhanced adiponectin, and increased expression of Cpt1a as well as other genes associated fatty acid oxidation [70,71]. A
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Pathogenesis of splenic infarcts depends on i e
2020-07-28
Pathogenesis of splenic infarcts depends on, i.e., etiology. Transient antiphospholipid (APL) RGFP966 have been associated with some viral infections, e.g., HIV, CMV, EBV, VZV, parvovirus B19. This was a most challenging case because of seemingly unrelated findings. Firstly, the patient had a past
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br Author contributions br Funding The QuantiFERON sample
2020-07-28
Author contributions Funding The QuantiFERON sample sets were provided by Qiagen, Hilden, Germany. Conflicts of interest Acknowledgments Background Congenital cytomegalovirus (cCMV) infection is common, with an estimated birth prevalence of 0.2% in US, Canada, Australia, and Western
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When animals are infected with
2020-07-27
When animals are infected with viruses a wide range of innate and adaptive immune responses are activated. Viral infection elicits broad changes in the type and amounts of protein made by the infected cell and thereby disrupt cellular homeostasis. In addition to production of viral proteins thapsiga
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br Obesity generally defined as a
2020-07-27
Obesity, generally defined as a body mass index (BMI) of ≥30 kg/m, is a major health problem in the United States, affecting ∼20% of adults . It is a risk factor for hypertension, diabetes, and cardiovascular disease. Health care costs attributable to obesity amount to ∼$100 billion annually . Des
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Information on in vitro metabolite profile
2020-07-27
Information on in vitro metabolite profile, pathways of BNZ metabolism and contribution of specific CYP450 isoforms towards its metabolism in human and rodent such as rat could be very valuable in order to understand the differences in metabolism among individuals as well as species differences in m
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CDK lacks DNA binding domains and
2020-07-27
CDK6 lacks DNA-binding domains and nuclear localization sequences, and therefore will probably be transported to the nucleus by a ‘piggy-back’ mechanism and needs to contact its specific sites indirectly through DNA-binding proteins. Besides NF-κB p65, a further candidate transcription factor is PAX
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We also identified a role for
2020-07-27
We also identified a role for the transcription factor p53 in the regulation of the Crm1 promoter. p53 can activate or repress the transcription of target genes. While activation generally occurs through binding of p53 to its consensus binding site in the promoter region of target genes, for example
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br Results and Discussion br Experimental
2020-07-27
Results and Discussion Experimental Procedures Acknowledgments Introduction Macromolecular exchange between the nucleus and the KW 3902 is an essential cellular process in all eukaryotes and occurs through the nuclear pore complexes (NPCs) embedded in the nuclear envelope. Most transport
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