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Cell adhesion molecules CAMs are
2018-10-26
Cell adhesion molecules (CAMs) are transmembrane proteins that are responsible for mediating adhesion of cells to other cells and/or the extracellular matrix via their extracellular domains, while their intracellular domain interacts with the cytoskeleton. Thus, CAMs provide a direct link between th
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In the present study we
2018-10-26
In the present study, we generated an Eva1a knockout (KO) mouse to study the physiological role of EVA1A in vivo. The analysis of Eva1a KO embryos and isolated NSCs revealed the function of EVA1A in self-renewal and neuronal differentiation of NSCs. Our study highlighted a previously unknown role of
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br Experimental Procedures br Author Contributions
2018-10-26
Experimental Procedures Author Contributions Acknowledgments We wish to thank Nicole Varain and Donna Colon for their excellent technical support assisting with the fetal sheep transplants. This work was supported by NIH, NHLBIR01HL097623, and the Intramural Pilot Program of Wake Forest Sch
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diazoxide ESCs were first discovered in
2018-10-26
ESCs were first discovered in 1981 independently by two groups (Martin, 1981; Evans and Kaufmann, 1981) and, while they were initially cultivated in medium containing physiological glucose (Glc) concentrations of 5.5 mM, descriptions of their routine cultivation in 25 mM Glc can be traced back to re
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br Results br Discussion Human HLCs derived from pluripotent
2018-10-26
Results Discussion Human HLCs derived from pluripotent stem apexbio are permissive to infection by hepatotropic viruses, including HCV and HBV. Interestingly, the SEC14L2 gene, an essential host factor for supporting the replication of wild-type, unadapted HCV genomes, was induced during the h
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Although we observed low overall rates of CNVs
2018-10-26
Although we observed low overall rates of CNVs, we observed five recurrently altered regions. Three of the intervals are quiescent, containing few (if any) regulatory elements and either low or unexpressed genes. However, one of these intervals (the chr16 interval) is recurrently aberrantly methylat
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The goal of this study was to understand how
2018-10-26
The goal of this study was to understand how synthetic hydrogels influence global biological function compared with standard 2D or 3D cell-culture formats. Vascular morphogenesis was chosen as a model biological system, and a bioinformatics approach was employed to provide genome-wide analysis for H
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br Introduction Retinoblastoma is the most
2018-10-26
Introduction Retinoblastoma is the most common primary intraocular pediatric cancer, with 95% of the cases diagnosed before 5 years of age (Kivela, 2009). Retinoblastoma is initiated by biallelic inactivation of the retinoblastoma 1 (RB1) gene. In heritable retinoblastoma, a primary germline muta
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br Experimental Commercial Luxeon Rebel ES LEDs produced
2018-10-26
Experimental Commercial Luxeon Rebel ES LEDs produced by Philips Lumileds have been the subject of our investigation. The area of the emitting chip was 1340 µm × 1340 µm. This device is known as the thin-film flip-chip InGaN/GaN multiple-quantum-well LED (TFFC LED) [3]. To provide efficient heat
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There is a growing interest in
2018-10-26
There is a growing interest in the impact of stress including cumulative adversity over the lifetime, and the physiological toll resulting from ongoing activation of stress responses at or around the time of childbearing (Phelan et al., 2015; Hobel, Goldstein, and Barrett, 2008; Dominguez et al., 20
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br Methods br Results The analyses
2018-10-26
Methods Results The analyses indicate how microscale pedestrian environment features varied by block group median income and race/ethnicity (Table 2). In all three regions, the findings revealed that norepinephrine reuptake inhibitor certain microscale pedestrian features were less favorable
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Fig displays associations between number of children and par
2018-10-26
Fig. 4 displays associations between number of children and parental weight from our a priori specified stratified analyses. Each graph presents the adjusted estimates from a stratified regression model; the sample size and P-values associated with the child count and the child-count/gender interact
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Table also shows the ancestral distribution of the sample by
2018-10-26
Table 1 also shows the ancestral distribution of the sample by generational status. For example, Column 1 shows that congo red among immigrants who arrived after age 13, individuals from the West Indies are the largest immigrant subgroup (proportion: 0.360) followed by immigrants from Africa (0.229)
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Marketing literature states that a beneficial or successful
2018-10-26
Marketing literature states that a beneficial or successful m-CRM can be influenced by different company resources, such as technological, economic, and human ones (e.g. employees and managers), as well as by its capacity and/or competence (Sarmaniotis, Assimakopoulos, & Papaioannou, 2013). Accordin
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retinoid x receptor Statistical comparisons between PSG and
2018-10-26
Statistical comparisons between PSG and actigraphy measures obtained from either the original or spline-modified data were performed using several methods: (1) Sleep summary measures obtained from the wrist and hip actigraphy recordings were compared with mean PSG values using a nonparametric Wilcox
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