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An equally important question is
2018-11-02
An equally important question is the role of LIF signaling in regulating the ESC cell cycle. Some target genes of the LIF/STAT3 pathway, such as c-myc, Klf4, Klf5, and Pim-1 (Aksoy et al., 2007; Bourillot et al., 2009), participate in regulating the G1-to-S phase transition in differentiated cells a
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In this study we employed APEL based
2018-11-02
In this study, we employed APEL-based differentiation to assess the contribution of WNT signaling to hematopoietic development from human embryonic stem cells. Although mesoderm formation was dependent upon WNT signals, WNT3A alone was an inefficient inducer of mesoderm. However, WNT3A synergized st
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The presence of condensin II at
2018-11-02
The presence of condensin II at enhancer/promoter sites occupied by the Mediator coactivator and NIPBL suggests that it is recruited to these sites during transcription activation. To test this model, we used a well-characterized cell system with a stably transfected doxycycline (Dox)-inducible tran
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microRNAs miRNAs are small noncoding RNAs
2018-11-02
microRNAs (miRNAs) are small noncoding RNAs of 22 nucleotides that control gene expression chiefly by translational repression (Lee et al., 2004). miRNA expression is spatially and temporally regulated during development, and they can participate in the regulation of pluripotent stem cell lineage co
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Studies from other glandular tissues like mammary gland reve
2018-11-02
Studies from other glandular tissues, like mammary gland, revealed CD24hi/CD29lo- (Shackleton et al., 2006) expressing a range of as potential stem cells. In mice, we reported that intraglandular transplantation of primary-sphere-derived CD24+/CD29+ cells could ameliorate radiation-induced hyposal
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Interestingly this study of WASp deficient iPSCs in
2018-11-02
Interestingly, this study of WASp-deficient iPSCs, in comparison with their corrected cWAS-iPSC counterparts, revealed not only the expected functional defects in certain iPSC-derived hematopoietic progeny (e.g., NK cells), but also identified potential consequences for WASp deficiency in T and NK d
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Future studies of human astrocyte response to inflammation r
2018-11-02
Future studies of human astrocyte response to inflammation require reliable in vitro models. Human astrocytes can be cultured from fetal and adult biopsies; however, the availability of CNS human tissue is reduced and immunopanning is required to obtain pure astrocyte preparations (Zhang et al., 201
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The device generates probing ultrasonic waves one longitudin
2018-11-02
The device generates probing ultrasonic waves [7] (one longitudinal and two transverse, polarized in mutually perpendicular directions) by piezoelectric transducers (PETs) serving as piezo-actuators. The reflected elastic waves excited in the material of the controlled object are also received by th
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Thus the Fe ion in the main three valence
2018-11-02
Thus, the Fe3+ ion in the main three-valence state possessing total spin 5/2 as revealed by ESR, is to have the 4s2(1)4p1(3) hybridization, whereas the neutral iron galanin receptor does not contain electrons in 4p-orbitals. So, the tetra-coordinated iron ion in the BSO crystal donates three valenc
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The effect of rotation rate on the energy spectrum
2018-11-02
The effect of rotation rate on the mth1 inhibitor spectrum of the vertical velocity component is illustrated by Fig. 5 (the monitoring point is located in the central horizontal plane, at a distance of 0.05Н from the adiabatic wall). The dimensionless oscillation frequency where f\' is the dimensi
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br Disc http www apexbt com media diy images
2018-11-02
Discussion We reported a case of a patient with diagnosis of MD1 and sleep central sleep Cy5.5 hydrazide syndrome, treated with Bilevel, showing improvement of the polysomnography parameters and some of the sleep-related symptoms. The presence of central apneas in patients with MD1 has been repor
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Speed of performance work rates number of problems
2018-11-01
Speed of performance [75], work rates ([17,24,98][87]), number of problems attempted [4,13,41]; Webb and Levy, 1984) and choice of tasks of various degrees of difficulty [7,79] have been used to determine performance effort. The subjective experience of effort is the sense of perceived exertion when
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br Conflict of interest br Acknowledgment br Introduction Re
2018-11-01
Conflict of interest Acknowledgment Introduction Recently much effort has been spent in the area of microarrays to bring this technology into non-research markets [6,25]. One of the drivers for technology is the demand for point-of-care diagnostics (POC) [18]. Several attempts have been mad
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Jalisco se encuentra entre los estados con mayores niveles
2018-11-01
Jalisco se encuentra entre los estados con mayores niveles educativos, de formación profesional y empleo de trabajadores del conocimiento, en tecnologías de la información y la comunicación en el país. En la ocupación de especialistas formados en carreras relacionadas con ingeniería en computación e
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This simple message of assessing
2018-11-01
This simple message of assessing the fall status in all preoperative patients will hopefully be adopted in daily clinical practice. Early identification of patients at risk of postoperative falls may enable preventative measures to be implemented before surgery to decrease the risk of postoperative
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