• br Introduction Prostate cancer strikes one in six

  2018-11-05

  

  Introduction Prostate cancer strikes one in six men and is the second leading cause of cancer-related deaths in men after lung cancer in the United States. Prostate cancer arises mainly from prostatic intraepithelial neoplasia (PIN), a precursor lesion that ultimately progresses to adenocarcinoma

• Previous work showed that lncRNAs show higher tissue

  2018-11-05

  

  Previous work showed that lncRNAs show higher tissue specificity compared to mRNAs (). The work of Ching et al. supported this notion, and extended it by showing a reduction of specificity after malignant transformation, which is consistent with the de-differentiation status of cancers widely observ

• br Search strategy and selection criteria

  2018-11-05

  

  Search strategy and selection criteria This review was prepared by searching in PubMed with querying key words: p16INK4a, epigenetics, alteration, gene alteration, gene silencing, cancer, promoter alteration and induction of p16INK4a. The search was conducted for research articles including clini

• The following are the supplementary data related

  2018-11-05

  

  The following are the supplementary data related to this article. Author Contribution Acknowledgments This study is supported in part by the Bureau of Health Promotion, Department of Health, R.O.C. (Taiwan) (DOH99-HP-1205), Taiwan Ministry of Health and Welfare Clinical Trial and Research Ce

• The fit of the structural model was good see

  2018-11-05

  

  The fit of the structural model was good (see Table 2) and confirms the hypotheses related to the direct influence of parental levels of regional ethnocentrism on children\'s levels of ethnocentrism and the hypotheses related to the influence of parental levels of regional identity on the children\'

• In a decisive effort to simplify the

  2018-11-05

  

  In a decisive effort to simplify the alkyd reactor prediction–estimation problem and all monitoring/control problems associated with it, a novel linear integral model for conversion of ampicillin sodium functional group was developed in this study for predicting the progress of reaction in a typica

• To support claims of benefit in terms

  2018-11-05

  

  To support claims of benefit, in terms of reduced environmental burden or increased process sustainability, rigorous process analysis is required using tools such as Life Cycle Assessment or carbon- and water footprinting. These approaches require availability of material and purchase LY2584702 inv

• Sleep is an important modulator of hormonal release

  2018-11-05

  

  Sleep is an important modulator of hormonal release, glucose regulation and cardiovascular function. In particular slow-wave sleep, the most restorative sleep stage, is associated with decreased heart rate, blood pressure, sympathetic nervous activity and cerebral glucose utilization, compared with

• Models that can both explain and evaluate

  2018-11-05

  

  Models that can both explain and evaluate sleep, while being usable in sleep education strategies are lacking [34]. These models are often based on sleep questionnaires. In the evaluation of sleep, questionnaires are a valid method to track sleep disturbances and can be used as reliable tools in dai

• Finally the relationship between age and average

  2018-11-05

  

  Finally, the relationship between age and average sleep time was U-shaped, with a minimum of 7.6h in subjects between 45 and 54 years of age and a maximum of 10h in those over 75 (Fig. 3). Discussion The overall prevalence of sleep complaints in Colombia (59%) is similar to that reported in the

• In addition to the CFU TCN

  2018-11-05

  

  In addition to the CFU, TCN, TOC and ATP measurements, the glass bead surface was examined by scanning electron microscopy (SEM) and examples are shown in Fig. 12, at magnifications of 5000. The SEM images indicate attachment of biofilm after day 1 but, in addition, also some detachment of biofilm b

• This study describes the development of an EW

  2018-11-05

  

  This study describes the development of an EW fiber-optic sensor for the detection of matrix metalloproteinase 2 (MMP-2) and 9 (MMP-9) activities. In the context of pressure and venous leg ulcers, an elevated and persistent activity of these proteases has been associated with a loss of extracellular

• br Introduction Immunosensors are a

  2018-11-05

  

  Introduction Immunosensors are a specific type of biosensors and can be defined as compact analytical devices that yield measurable signals in response to specific antibody–antigen interactions. A large number of immunosensors have been developed using different kinds of transducers that exploit

• Although the beneficial effects of

  2018-11-03

  

  Although the beneficial effects of LXR signaling have been suggested to play a key role in vascular diseases such as atherosclerosis and diabetes, the mechanism of action in which LXR activation influences inflammation and cholesterol metabolism remains an active area of investigation. LXR activity

• Specifications Table br Data The data set used in

  2018-11-03

  

  Specifications Table Data The data set used in the study involves the experimental results indicating the inducible effects of exogenous exposure of salicylic kinesin spindle protein and methyljasmonate on the three NMT transcripts. The data also supplements the study describing the ability of

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