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From the point of view of
2018-10-29
From the point of view of the impact of modernity, we could conclude that the Xianxian-Daming handbook is rather conservative. On the one hand, the Western authors refused inculturation and any stylistic evolution to a Sino-Christian style. On the other hand, they say nothing about modern techniques
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This online bulletin board and blog
2018-10-29
This online bulletin board and blog allowed motilin receptor members to post their contact information followed by comments or questions. Discussion board entries were posted live. The design team monitored the site and responded to questions and concerns. Data entered into the website were recorde
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Preoperative imaging modalities such as contrast enhanced ab
2018-10-29
Preoperative imaging modalities, such as contrast-enhanced abdominal CT, facilitate diagnosis. Helical CT plays a crucial role in the diagnosis of intraluminal or exophytic tumors. The differential diagnosis of GI tract tumors should include fibromatosis, leiomyoma, schwannoma, inflammatory fibroid
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The identification of new stem cell
2018-10-29
The identification of new stem cell markers characteristic of a phenotypic subset or experimental state remains a major LJI308 research goal. Researchers may wish to assess the uniqueness of an expression profile before embarking on experiments that rely on a reporter gene or antibody to select for
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In the present study we tested five different pharmacologica
2018-10-29
In the present study, we tested five different pharmacological agents that are commonly used as selective inhibitors of Nodal/Activin signaling, namely SB431542, LY364947, A-83-01, SB505124, and SB525334 (Inman et al., 2002; Callahan et al., 2002; Laping et al., 2002; DaCosta Byfield et al., 2004; L
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Most studies investigating cardiomyocyte differentiation
2018-10-29
Most studies investigating cardiomyocyte differentiation from ESCs have used isoprenaline and carbachol as the “standard” agonists to confirm that the physiological or electrophysiological properties of the derived cardiomyocytes resemble native tissue (Banach et al., 2003; He et al., 2003; Fu et al
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Partitioning of the dorsal telencephalon centers
2018-10-29
Partitioning of the dorsal telencephalon centers on the paired-box transcription factor Pax6. At the neural plate stage in the mouse, Pax6 expression is observed throughout the telencephalic anlagen, with later expression restricted primarily to the dorsal pallium neocortex domain (Pax6 expression h
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In this study we have employed mouse NSCs rather
2018-10-29
In this study, we have employed mouse NSCs rather than human NSCs to explore the effects of PA. In view of this, further study would be desirable to ascertain if comparable effects of PA occur in human NSCs. In addition, elevated FFA level is intimately associated with oxidative stress and high leve
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Both Brat and Mei P belong
2018-10-29
Both Brat and Mei-P26 belong to the Trim-NHL family of proteins, which have conserved functions in stem cell lineages from C. elegans to mouse (for review, see Wulczyn et al., 2010). Proteins within this family are potential E3 ubiquitin ligases and can act by either activating or antagonizing the m
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br Experimental Procedures br Acknowledgments
2018-10-29
Experimental Procedures Acknowledgments This work was supported by BONFOR/Gerok Scholarships O-137.0015 (to B.V.S.), Ruediger Foundation grants (to B.V.S.), State Scholarship Fund/Chinese Scholarship Council 2008627116 (to Z.L.), NIH – National Eye Institute 5R01EY022079-02 (to S.T.), and NYSD
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In our previous study we reported
2018-10-26
In our previous study, we reported a genetic diagnosis of a GT patient with two different mutations in the two ITGA2B alleles. Both mutations activated a same recessive intron splicing site and cause a 99-base deletion in IIb mRNA (Li et al., 2011). In the current study, we successfully established
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Cell adhesion molecules CAMs are
2018-10-26
Cell adhesion molecules (CAMs) are transmembrane proteins that are responsible for mediating adhesion of cells to other cells and/or the extracellular matrix via their extracellular domains, while their intracellular domain interacts with the cytoskeleton. Thus, CAMs provide a direct link between th
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In the present study we
2018-10-26
In the present study, we generated an Eva1a knockout (KO) mouse to study the physiological role of EVA1A in vivo. The analysis of Eva1a KO embryos and isolated NSCs revealed the function of EVA1A in self-renewal and neuronal differentiation of NSCs. Our study highlighted a previously unknown role of
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br Experimental Procedures br Author Contributions
2018-10-26
Experimental Procedures Author Contributions Acknowledgments We wish to thank Nicole Varain and Donna Colon for their excellent technical support assisting with the fetal sheep transplants. This work was supported by NIH, NHLBIR01HL097623, and the Intramural Pilot Program of Wake Forest Sch
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diazoxide ESCs were first discovered in
2018-10-26
ESCs were first discovered in 1981 independently by two groups (Martin, 1981; Evans and Kaufmann, 1981) and, while they were initially cultivated in medium containing physiological glucose (Glc) concentrations of 5.5 mM, descriptions of their routine cultivation in 25 mM Glc can be traced back to re
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