• Repurposing use of approved drugs for new indications

  2019-04-23

  

  Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o

• La imagen de la Virgen de Caacup junto con

  2019-04-23

  

  La imagen de la Virgen de Caacupé junto con sus celebraciones religiosas y su devoción llegó a la ciudad en 1993 en forma de obsequio de una compatriota paraguaya a la agrupación arpa. A partir de entonces, la colectividad incorporó la práctica religiosa devocional no sólo como uno de los actos más

• M s all de la interconexi n entre la estructura

  2019-04-23

  

  Más allá de la interconexión entre la estructura exportadora y los factores de la economía nacional que nos plantea aristas más que interesantes, así como también de la relación de los componentes que hacen Protease Inhibitor Library la conservación del patrón de especialización primaria, no podemos

• Finally the effects of In NLS CSL on hematopoietic function

  2019-04-23

  

  Finally, the effects of 111In-NLS-CSL360 on hematopoietic function in healthy Balb/c mice was studied. Groups of 2–4 mice were injected i.v. with 6.1±1.4MBq, 18.8±1.5MBq or 35.8±0.9MBq of 111In-NLS-CSL360 or an equivalent mass (70μg) of unlabeled CSL360 or received normal saline. At two weeks post-t

• There are some models of sleep

  2019-04-23

  

  There are some models of sleep deprivation, such as acute or chronic, total or selective sleep deprivation, sleep restriction, or sleep fragmentation. Modifed multiple platform method (MMPM) in our study causes a particularly strong reduction in REM sleep, breaks the sleep continuity. Previous studi

• br In December consecutive waves of major smog

  2019-04-22

  

  In December, 2016, consecutive waves of major smog shrouded China, particularly the North China Plain and Sichuan Basin, resulting in suspended schools, halted industrial production, and heavy traffic. Atmospheric levels of fine particulate tlr signaling (PM) spiked to more than 500 μg/m in Henan

• In terms of outcome based assessments

  2019-04-22

  

  In terms of outcome-based assessments, we analyzed the primary outcomes in both the 7-day and in-hospital mortality, to evaluate further whether the cause of death would be related to acute illness or chronic comorbidities, and furthermore to ensure care quality in both units. Illness severity and t

• br Discussion Rarely a breast

  2019-04-22

  

  Discussion Rarely, a breast cancer patient has histologically proven breast cancer found outside the breast without a detectable primary breast tumor. Almost always the site of detected disease is an axillary lymph node. The incidence of axillary breast cancer with occult primary is relative low,

• br Discussion Early repolarization is a

  2019-04-22

  

  Discussion Early repolarization is a common ECG characteristic. Its reported prevalence is 6–25% of the general population, and is particularly common in athletes [2,3,11,12]. It is now recognized that a small fraction of people with early repolarization on their ECGs develop lethal tachyarrhythm

• br Materials and methods br Results br

  2019-04-22

  

  Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between

• We are aware that physician surveys have been previously use

  2019-04-22

  

  We are aware that physician surveys have been previously used to assess; bisphosphonate use for bone pain [14], bisphosphonate use in metastatic breast cancer patients [15] and radiotherapy use for painful bone metastases [16] but are not aware of physician surveys being used to help design trials o

• monensin br Conclusion br Limitations br Conflict of interes

  2019-04-22

  

  Conclusion Limitations Conflict of interest Introduction The prevalence of monensin failure prevalence is increasing throughout the world. The reasons for this pandemic include the aging populations of both industrialized and developing nations and a growing incidence of obesity, diabete

• br The paper in by Victoria Fan

  2019-04-22

  

  The paper in by Victoria Fan and colleagues is important because it describes what several people close to the Global Fund to fight AIDS, Tuberculosis and Malaria already know: there is a problem with its disbursement mechanisms. Fan and colleagues correctly state that the Global Fund should “red

• In the context of our present work that uses

  2019-04-22

  

  In the context of our present work that uses total community treatment with azithromycin for yaws eradication, we would support an empirical approach to treatment. Azithromycin is effective for treatment of both and , so our mass treatment should be effective for both causes of skin ulcer. isolate

• El estudio se realiza desde una

  2019-04-22

  

  El estudio se realiza desde una perspectiva cualitativa, Fluorouracil partir del análisis del discurso de entrevistas a miembros de los movimientos sociales, así como de declaraciones, discursos y otros textos vinculados tanto a gobiernos, como a los movimientos y sus respectivos proyectos y espacio

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